Delayed onset of action1
Cycling through monoaminergic antidepressants reduced rates of remission with each treatment step2*
55% of patients experienced “bothersome”
side effects3
*Remission defined as QIDS-SR16 score ≤5 at exit from the indicated treatment step.
MDD=major depressive disorder; QIDS-SR=Quick Inventory of Depressive Symptomatology-Self Report; STAR*D=Sequenced Treatment Alternatives to Relieve Depression study.