Do not share your Ozempic^® pen with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them.

What is the most
important information
I should know about
Ozempic^®?

Ozempic^® may cause
serious side effects,
including:

• Possible thyroid
tumors, including
cancer. Tell your
health care provider if
you get a lump or
swelling in your neck,
hoarseness, trouble
swallowing, or
shortness of breath.
These may be
symptoms of thyroid
cancer. In studies with
rodents, Ozempic^® and
medicines that work
like Ozempic^® caused
thyroid tumors,
including thyroid
cancer. It is not known
if Ozempic^® will cause
thyroid tumors or a
type of thyroid cancer
called medullary
thyroid carcinoma
(MTC) in people.

• Do not use Ozempic^® if
you or any of your
family have ever had
MTC, or if you have an
endocrine system
condition called
Multiple Endocrine
Neoplasia syndrome
type 2 (MEN 2).

What is Ozempic^®?

Ozempic^® (semaglutide)
injection 0.5 mg, 1 mg,
or 2 mg is an injectable
prescription medicine
used:

• along with diet and
exercise to improve
blood sugar (glucose)
in adults with type 2
diabetes.

• to reduce the risk of
major cardiovascular
events such as heart
attack, stroke, or death
in adults with type 2
diabetes with known
heart disease.

It is not known if
Ozempic^® can be used in
people who have had
pancreatitis.

Ozempic^® is not for use
in people with type 1
diabetes.

It is not known if
Ozempic^® is safe and
effective for use in
children under 18 years
of age.

Do not use Ozempic^® if:

• you or any of your
family have ever had
MTC or if you have
MEN 2.

• you are allergic to
semaglutide or any of
the ingredients in
Ozempic^®. See
symptoms of serious
allergic reaction in
"What are the possible
side effects of
Ozempic^®?".

Before using Ozempic^®,
tell your health care
provider if you have
any other medical
conditions, including if
you:

• have or have had
problems with your
pancreas or kidneys.

• have a history of
diabetic retinopathy.

• are pregnant or
breastfeeding or plan
to become pregnant or
breastfeed. It is not
known if Ozempic^® will
harm your unborn
baby or passes into
your breast milk. You
should stop using
Ozempic^® 2 months
before you plan to
become pregnant.

Tell your health care
provider about all the
medicines you take,
including prescription
and over-the-counter
medicines, vitamins,
herbal supplements, and
other medicines to treat
diabetes, including
insulin or sulfonylureas.

What are the possible
side effects of
Ozempic^®?

Ozempic^® may cause
serious side effects,
including:

• inflammation of your
pancreas (pancreatitis).
Stop using Ozempic^®
and call your health
care provider right
away if you have
severe pain in your
stomach area
(abdomen) that will not
go away, with or
without vomiting. You
may feel the pain from
your abdomen to your back.

• changes in vision. Tell
your health care
provider if you have
changes in vision
during treatment with
Ozempic^®.

• low blood sugar
(hypoglycemia). Your
risk for getting low
blood sugar may be
higher if you use
Ozempic^® with another
medicine that can
cause low blood sugar,
such as a sulfonylurea
or insulin. Signs and
symptoms of low
blood sugar may
include: dizziness or
lightheadedness,
blurred vision, anxiety,
irritability or mood
changes, sweating,
slurred speech,
hunger, confusion or
drowsiness, shakiness,
weakness, headache,
fast heartbeat, and
feeling jittery.

• kidney problems
(kidney failure). In
people who have
kidney problems,
diarrhea, nausea, and
vomiting may cause a
loss of fluids
(dehydration), which
may cause kidney
problems to get worse.
It is important for you
to drink fluids to help
reduce your chance of
dehydration.

• serious allergic
reactions. Stop using
Ozempic^® and get
medical help right
away if you have any
symptoms of a serious
allergic reaction,
including swelling of
your face, lips, tongue,
or throat; problems
breathing or
swallowing; severe
rash or itching; fainting
or feeling dizzy; or very
rapid heartbeat.

• gallbladder problems.
Gallbladder problems
have happened in
some people who take
Ozempic^®. Tell your
health care provider
right away if you get
symptoms which may
include: pain in your
upper stomach
(abdomen), fever,
yellowing of the skin or
eyes (jaundice), or
clay-colored stools.

The most common side
effects of Ozempic^®
may include nausea,
vomiting, diarrhea,
stomach (abdominal)
pain, and constipation.

Please see Prescribing
Information and
Medication Guide.

Ozempic^® is a
prescription medication.

Novo Nordisk provides
patient assistance for
those who qualify.
Please call
1-866-310-7549 to learn
more about Novo
Nordisk assistance
programs.

You are encouraged to
report negative side
effects of prescription
drugs to the FDA. Visit
www.fda.gov/medwatch
or call 1-800-FDA-1088.

Ozempic^® is a registered
trademark of Novo
Nordisk A/S.

Novo Nordisk is a
registered trademark of
Novo Nordisk A/S.

^© 2023 Novo Nordisk
All rights reserved.
US23OZM00106
September 2023

Important Safety Information