br.not-default {
  display: none;
}

.text-center {
  text-align: center;
}

#container_ad,
#container_anim,
#chromeCover,
#clickScreen {
  position: absolute;
  width: 728px;
  height: 90px;
}

.reference-wrap .with-ref, .footnote-wrap .with-ref {
  padding-left: 4px;
  position: relative;
}
.reference-wrap .with-ref sup:first-of-type, .footnote-wrap .with-ref sup:first-of-type {
  position: absolute;
  left: 0;
  top: 3px;
}
html,
body,
* {
  padding: 0;
  margin: 0;
}

#container_ad {
  overflow: hidden;
  border: 1px solid #B5B5B5;
  box-sizing: border-box;
}

#container_anim {
  left: -1px;
  top: -1px;
}

#chromeCover {
  background-color: #ffffff;
}

.fontSize-11 {
  font-size: 11px;
}

.fontSize-14 {
  font-size: 14px;
}

.fontSize-15 {
  font-size: 15px;
}

.fontWeight-bold {
  font-weight: 700;
}

.color-purple {
  color: #61279e;
}

sup,
sub {
  line-height: 0px;
}

h1,
h2,
h3 {
  font-family: "Barlow Semi Condensed";
  color: #fff;
  font-weight: 600;
}
h1.medium,
h2.medium,
h3.medium {
  font-weight: 400;
}

h1 {
  font-weight: 700;
}
h1.medium {
  font-weight: 400;
}

sup {
  font-size: 50%;
}

.ref {
  margin-left: 5px;
}
.ref sup:first-of-type {
  margin-left: -5px;
}
@charset "UTF-8";
#logo-servier-isi {
  width: 100%;
  max-width: 160px;
  height: auto;
  display: block;
  margin: 16px auto 12px;
}

.sectionBorder {
  border: 1.5px solid #636466;
  padding: 7px;
}

.listItem-bull {
  margin-left: 12px;
}
.listItem-bull::before {
  content: "•";
  margin-right: 4px;
  margin-left: -8px;
  font-size: 12px;
  line-height: 11px;
}

.iScrollLoneScrollbar {
  width: 4px;
  overflow: initial !important;
  background-color: #565757;
  border-radius: 5px;
  border-bottom: 3px solid #565757;
}

.iScrollVerticalScrollbar .iScrollIndicator {
  width: 2px;
  background-color: #ffffff;
  border-radius: 5px;
  left: 1px;
  top: 1px;
}

#containerISI,
#isiContent,
#isiPiBottom,
.iScrollVerticalScrollbar,
.iScrollIndicator {
  position: absolute;
}

.iScrollVerticalScrollbar {
  bottom: 22px;
  top: 8px;
  right: 8px;
}

#isiContent {
  background-color: #ffffff;
  overflow: hidden;
  height: 100%;
  width: 100%;
}

#containerISI {
  bottom: 0;
  font-family: "Barlow Semi Condensed", sans-serif;
  color: #636466;
  font-size: 12px;
  width: 220px;
  height: 90px;
  right: 0px;
}

#scroller {
  width: 95%;
  width: calc(100% - 30px);
  padding: 5px 5px 16px 5px;
}
#scroller p {
  margin-bottom: 6px;
}
#scroller p.isiHeading {
  padding-top: 6px;
}
#scroller .long-url {
  word-break: break-word;
}
#scroller .footnote-wrap,
#scroller .reference-wrap {
  padding-top: 6px;
  margin-bottom: 0;
}
#scroller .footnote-wrap p,
#scroller .reference-wrap p {
  margin-top: 0;
  margin-bottom: 0;
}
#scroller .footnote-wrap {
  margin-bottom: 6px;
}
#scroller .endMatter {
  margin-top: 6px;
  margin-bottom: 0;
}
#scroller .endMatter:last-of-type {
  padding-bottom: 6px;
}

#isiPiBottom {
  font-family: "Barlow Semi Condensed", sans-serif;
  background-color: #565757;
  text-align: left;
  width: 100%;
  bottom: 0;
  display: inline-block;
  padding-right: 3px;
  padding-left: 5px;
  padding-top: 1px;
  height: 16px;
  font-size: 12px;
  line-height: 13px;
  color: #ffffff !important;
  opacity: 0;
  visibility: hidden;
}
#isiPiBottom a {
  padding-bottom: 3px;
  padding-top: 3px;
  color: #ffffff !important;
}
#isiPiBottom span {
  font-size: 11px;
}
br.not-default {
  display: none;
}

#container_ad,
#container_anim,
#container_anim > div,
#container_anim div img,
svg,
#chromeCover,
#clickScreen {
  position: absolute;
  width: 728px;
  height: 90px;
}

#servier_logo {
  position: absolute;
  width: 121px;
  bottom: 110px;
  left: 90%;
  left: calc(100% - 12px);
  opacity: 0;
}

#cta {
  display: block;
  position: absolute;
  bottom: 118px;
  left: 5%;
  opacity: 0;
  font-family: "Barlow Semi Condensed", Arial;
  font-size: 14px;
  font-weight: 700;
  color: #61279e;
  padding: 5px 20px 5px 40px;
  border-radius: 20px;
  background-color: #fff;
  text-decoration: none;
}
#cta img {
  position: absolute;
  left: -1px;
  top: -1px;
  height: 29px;
  width: 29px;
}

.strokeDashoffset_0 {
  stroke-dashoffset: 0 !important;
}

#bg_img div {
  display: block;
  height: 0px;
  width: 100%;
  position: absolute;
  bottom: 0;
}

.gradient {
  background: rgb(97, 39, 158);
  background: linear-gradient(90deg, rgb(97, 39, 158) 0%, rgb(211, 67, 34) 80%, rgb(211, 67, 34) 100%);
}

#containerISI {
  visibility: hidden;
  opacity: 0;
  z-index: 1;
}

#text01_1 {
  position: relative;
}
#text01_1 h3 {
  position: absolute;
  padding-left: 25%;
  width: 65%;
  left: 100%;
  padding-right: 5%;
  top: 125px;
  font-size: 17px;
}
#text01_2 {
  position: relative;
}
#text01_2 h1 {
  position: absolute;
  font-weight: 600px;
  width: 65%;
  padding-left: 25%;
  left: 100%;
  padding-right: 5%;
  top: 160px;
  letter-spacing: -1px;
}

#text02 {
  position: relative;
}
#text02_1 {
  position: absolute;
  left: 100%;
  top: 15px;
  opacity: 0;
}
#text02_1 h2 {
  width: 90%;
  padding-right: 5%;
  padding-left: 5%;
}
#text02_2 {
  position: absolute;
  left: 100%;
  top: 40px;
  opacity: 0;
  padding-left: 5%;
}
#text02_2 h2 {
  width: 90%;
  padding-right: 5%;
  padding-left: 5%;
}
h1 {
  font-size: 29px;
  line-height: 29px;
}

h2 {
  font-size: 19px;
  line-height: 24px;
}

h3 {
  font-size: 14px;
  line-height: 18px;
}

#containerISI #isiContent {
  width: 220px;
  position: absolute;
  right: 0;
}
#containerISI #isiContent #scroller {
  z-index: 2;
}

#text01_1 h3 {
  top: 15px;
  padding-left: 34%;
  width: 95%;
}
#text01_2 h1 {
  top: 35px;
  padding-left: 34%;
  width: 95%;
}

#text02_1 {
  top: 5px;
}
#text02_1 h2 {
  padding-left: 13px;
  width: 100%;
}
#text02_2 {
  top: 27px;
}
#text02_2 h2 {
  padding-left: 13px;
  width: 260px;
  line-height: 20px;
}

#servier_logo {
  bottom: unset;
  top: 15px;
  right: 120px;
  left: unset;
}

.iScrollVerticalScrollbar {
  bottom: 5px;
}

#cta {
  top: 25px;
  left: 230px;
  height: 18px;
  padding: 5px 15px 5px 35px;
}

#isiPiBottom {
  width: 498px;
}

#clickScreen {
  width: 100%;
  height: 72px;
}