About CAPLYTA® (lumateperone) Skip to Main Content For US Residents Only Visit US Healthcare Professionals Site Important Safety Information Important Safety Information Prescribing Information Medication Guide Other Indications Cost & Savings Menu About Schizophrenia About Caplyta Common Side Effects Taking Caplyta Support & Resources Talking to a healthcare provider Patient & caregiver support Frequently asked questions Cost & Savings About Schizophrenia About Caplyta Common Side Effects Taking Caplyta Support & Resources Talking to a healthcare provider Patient & caregiver support Frequently asked questions Learn about speaking with a healthcare provider For US Residents Only Other Indications Visit US Healthcare Professionals Website About Caplyta CAPLYTA is a once-daily pill that is proven to help control symptoms of schizophrenia Actor portrayals. Schizophrenia is complicated, and so is treating it. If you struggle with symptoms or side effects that bother you, ask your healthcare provider if CAPLYTA may be right for you. In 2 studies, people who took Caplyta showed: Improved symptoms Overall Symptoms CAPLYTA was significantly better than sugar pill (placebo) at managing schizophrenia symptoms. Improved overall severity Overall Severity People taking CAPLYTA showed an improvement in the overall severity of their condition, measured on a schizophrenia rating scale. How CAPLYTA may work Chemical Messenger Although the exact cause of schizophrenia is unknown, it is believed that a chemical imbalance in the brain is the cause. These chemicals, known as "neurotransmitters," are dopamine, serotonin, and glutamate. Schizophrenia can result from abnormal interactions among these neurotransmitters. Schizophrenia is complicated. Although the exact way CAPLYTA works is unknown, it is thought to affect different brain-signaling chemicals to help control schizophrenia symptoms. Edgar's story The Balancing Act ® is a morning show that airs daily on the Lifetime network. One episode explores the challenges of treating schizophrenia from the point of view of both doctors and patients. In the video, two well-known doctors in the field of psychiatry—along with a person living with schizophrenia—speak openly about their experiences. Chapters: About schizophrenia About CAPLYTA View video transcript CAPLYTA® (lumateperone) savings card Savings Offer & Cost* Explore ways you might save on CAPLYTA Common Side Effects Find out what to expect when taking CAPLYTA *Please see Eligibility Requirements and Terms & Conditions Terms of Use Privacy Policy Cookie Policy Contact Us ITCI Corporate Site Sitemap Your Privacy Choices AdChoices Opt-Out © Johnson & Johnson and its affiliates 2025. CAPLYTA and LET IN THE LYTE are trademarks of Johnson & Johnson and its affiliates. Trademarks listed are the property of their respective owners. 11/25 US-CAP-2500313